Volume 1 ; Issue 1 ; in Month : Jan-June (2017) Article No : 105
Igor M Ignatyev and Elena E Fomina

Abstract

Objective: To develop the method of preventive diagnosis of venous thrombosis using the ultrasound duplex scanning (USDS). Materials and methods: 306 persons were examined, 146 were patients with acute venous thrombosis, 108 patients � with varicose veins and 52 healthy persons (control group). All participants were examined using USDS and D-dimer level was evaluated. Results: As the result of the conducted research an ultrasound phenomenon of echogenic particles in valvular sinus area (further referred to as spontaneous echo contrast) is described. A classification of this phenomenon is developed; two degrees of spontaneous echo contrast are documented. Spontaneous echo contrast of the 1st degree reflects the fact that the valvular sinus area is the most thrombogenic zone. Spontaneous echo contrast of the 2nd degree is characterized as pathological, it is a prethrombotic state and can serve as one of the most early predictors of developing venous thrombosis. A high correlation between phenomenon of spontaneous echo contrast of the 2nd degree, venous thrombosis and D-dimer level indicators is determined (r=0.89, P<0.05). Conclusions: An ultrasound study of valvular sinus is a simple, available and reproducible method of screening and can be applied as a preventive diagnostic of acute venous thrombosis. The results of the investigations permit us to form risk groups of deep vein thrombosis and perform timely prevention of this pathology.

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