Volume 2 ; Issue 1 ; in Month : Jan-Jun (2018) Article No : 114
Srivastava P, Kulkarni V, Khare J

Abstract

Cushing’s syndrome (CS) is a condition caused by prolonged exposure to elevated levels of glucocorticoids either endogenous or exogenous. The most common cause of CS is exogenous and depends on frequency and spectrum of medical condition which require glucocorticoid treatment. Exogenous CS is usually identified on the basis of history and laboratory studies. In our case a 55-year old female presented with complains of generalized weakness, easy fatigability, joint pain, generalized body swelling and facial puffiness with recent history of hypertension and diabetes. On clinical examination, she had truncal obesity moon facies, acanthosis nigricans, truncal obesity, pedal edema and high blood pressure. On enquiry patient gives history consumption of some medications for joint pain since last 6 months. She had persistent hypokalemia and high blood sugars. So, on clinical and biochemical features exogenous CS was suspected. Her morning 8 am serum Cortisol levels were 0.96ug/dl which was strongly suggestive exogenous CS. The patient showed clinical and biochemical improvement after stopping of all other medications.

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